Due to the discontinuation of ChemAxon support for academic websites, SwissSimilarity has been modified to no longer rely on their software.
The most frequently used compound libraries have already been re-prepared using RDKit and are now available. We are actively working to make the remaining libraries available as soon as possible.
We sincerely apologize for any inconvenience this transition may cause and thank our users for their understanding.

Don't know where to start? Try with an example Diclofenac, Propranolol or Nilotinib.

1 - Enter a molecule in SMILES format
  No SMILES available? Draw a molecule using the sketcher

Not a valid SMILES.

2 - Select a class of compounds


3 - Select compound library and screening method

4 - Submit

(Provide a query molecule, and select a compound library and a screening method before submitting)